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MDCM 599: Clinical Application of Basic Science (1 )
This course is an inter-departmental, team-based, technology-centric elective course. Concomitantly, instructors from the basic and clinical science departments within the school of pharmacy will promote deeper student understanding of the path a drug takes from discovery, development and ultimately clinical use. Instructors will collaborate in course content development to integrate basic and clinical science concepts. The course will utilize a blended learning method, incorporating out of class podcasts, online group collaborative projects, cloud-based file sharing, and readiness quizzes and exams. (Same as P&TX 599 and PHCH 599.) Prerequisite: 4th or 5th professional year standing (4P/5P) in the School of Pharmacy and concomitant enrollment in PHPR 599 is required. LEC
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MDCM 601: Medicinal Biochemistry I (4 )
A study of the biochemical principles of macromolecular structure and function, molecular communication, and the metabolism of nutrients and xenobiotics as applied to problems of medicinal and pharmacological significance. Prerequisite: Concurrent enrollment in MDCM 602 Lab. LEC
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MDCM 602: Medicinal Biochemistry Laboratory (1 )
Laboratory exercises illustrating the application of chemical principles to biochemical processes of medicinal, pharmacological, and clinical significance. Prerequisite: Concurrent enrollment in MDCM 601. LAB
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MDCM 603: Medicinal Biochemistry II (3 )
A study of the biochemical principles of macromolecular structure and function, biosynthesis, molecular communication, and the metabolism of nutrients and xenobiotics as applied to problems of medicinal and pharmacological significance. Prerequisite: MDCM 601. LEC
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MDCM 606: Phytomedicinal Agents (1 )
This course will acquaint the pharmacy students with the current status of botanical use in the United States. A basic foundation will be provided so that the pharmacist can properly assess the appropriateness and usefulness of various phytomedicines and combinations in managing certain ailments with regard to efficacy, safety, potential toxicity, and potential herb-drug interactions. Prerequisite: MDCM 626 or instructor permission. LEC
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MDCM 607: Clinical Pharmacognosy (1 )
The course will provide a technical background for understanding the scientific basis underlying the use of herbal medicines. This will be followed by practical information about the pharmacological and chemical properties as well as clinical uses of herbal medicines. Active student participation in discussing the properties of these non-prescription medicinals is expected. Prerequisite: MDCM 601. LEC
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MDCM 625: Medicinal Chemistry I: Neuroeffector Agents (3 )
A study, from the molecular viewpoint, of the organic substances used as medicinal agents, including consideration of their origins, chemical properties, structure-activity relationships, metabolism and mechanisms of action; this course emphasizes drugs affecting the central nervous system. Prerequisite: CHEM 626 and MDCM 601. LEC
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MDCM 626: Medicinal Chemistry II: Homeostatic Agents (3 )
A continuation of MDCM 625 with emphasis on autonomic and cardiovascular agents and peripherally-acting hormones. Prerequisite: MDCM 625. LEC
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MDCM 627: Medicinal Chemistry III: Chemotherapeutic Agents (3 )
A continuation of MDCM 625 and MDCM 626 with special emphasis on anticancer, antiviral, antibacterial, antifungal and non-steroidal anti-inflammatory drugs. Prerequisite: MDCM 625. LEC
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MDCM 675: Introduction to Drug Design and Development (2-3 )
A discussion of the principles of contemporary drug design with specific examples chosen from the original literature. Prodrugs: bioisosteres; modulation of drug absorption, distribution, metabolism, and excretion; molecular dissection; rigid analogs; pharmacophores; etc., will be treated. Prerequisite: MDCM 627. LEC
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MDCM 690: Undergraduate Research (1-5 )
Research in medicinal chemistry. Students will be assigned to a laboratory research problem. Prerequisite: Consent of instructor. IND
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MDCM 691: Research Techniques in Medicinal Chemistry (1 )
A lecture course designed to acquaint beginning research students with basic laboratory techniques, principles of laboratory safety, use of instrumental methods for structure elucidation, and the writing of scientific reports. Prerequisite: Consent of instructor. LEC
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MDCM 692: Problems in Medicinal Chemistry (1-5 )
This course encompasses original work on a laboratory problem of limited scope, honors reading assignments from medicinal chemistry literature, or in-depth discussions of assigned topics. Prerequisite: Consent of instructor. IND
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MDCM 701: Biomedicinal Chemistry (3 )
A study of the principles of macromolecular structure and function, biosignaling, bioenergetics and metabolism, with an emphasis on the relationship between biochemistry and medicine. Prerequisite: Graduate standing or permission of instructor. LEC
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MDCM 703: Advanced Biomedicinal Chemistry (3 )
A study of the principles of basic enzymology, including chemical reactions, biosynthesis, and metabolism. In addition, the course will cover lipids, hormones, vitamins, and minerals. Prerequisite: Graduate standing or permission of instructor. LEC
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MDCM 710: Physiological Aspects of Medicinal Chemistry (1 )
The goal of this one-credit-hour course is to provide an overview of physiological mechanisms and disease processes as a background for intermediate level courses in medicinal chemistry, drug discovery and drug development. Prerequisite: One college-level course in biology. LEC
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MDCM 721: Introduction to Medicinal Chemistry (1 )
An overview of the field of medicinal chemistry, including discussions of research techniques and the application of organic chemistry to medicinal chemistry problems. Prerequisite: Graduate standing or permission of instructor. LEC
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MDCM 722: Principles of Organic Medicinal Chemistry (3 )
The discovery and properties of pharmaceutical agents, including a survey of the various drug classes important in clinical applications. The relationship between chemical structure and biological mechanism of action will be emphasized. Prerequisite: Graduate standing or permission of instructor. LEC
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MDCM 725: Medicinal Chemistry I (2 )
A study, from the molecular viewpoint, of the organic substances used as medicinal agents, including consideration of their origins, chemical properties, structure-activity relationships, metabolism and mechanisms of action; this course emphasizes drugs affecting the central nervous system. Prerequisite: CHEM 626 and MDCM 621. LEC
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MDCM 726: Medicinal Chemistry II (2 )
A continuation of MDCM 725 with emphasis on autonomic and cardiovascular agents and peripherally-acting hormones. Prerequisite: MDCM 725. LEC
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MDCM 727: Medicinal Chemistry III (2 )
A continuation of MDCM 725 and MDCM 726 with special emphasis on anticancer, antiviral, antibacterial, antifungal and non-steroidal anti-inflammatory drugs. Prerequisite: MDCM 725. LEC
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MDCM 742: Experimental Pharmacology (4 )
Experimental approaches to understanding mechanism of drug action. Use of drugs as tools to understand functioning of biological systems will also be stressed. Historically important experiments will be discussed along with experiments which are currently used to define drug mechanisms. Topics will include: dose-response, drug receptors, drug metabolism, chemotherapy as well as autonomic CNS, cardiovascular and renal pharmacology. (Same as P&TX 742.) Prerequisite: Graduate standing in Medicinal Chemistry. LEC
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MDCM 766: Organic Chemistry of Biological Pathways (2 )
An introductory graduate level course in bioorganic and medicinal chemistry, in which the principles of organic reaction mechanisms in biological systems are discussed. This course discusses the organic chemistry of metabolic transformations of biomolecules and their associated cofactors, both organic coenzymes and metal ions. LEC
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MDCM 775: Chemistry of the Nervous System (3 )
A detailed study of the molecular aspects of nerve transmission will be covered with special emphasis on the uptake, storage, release, biosynthesis, and metabolism of specific neurotransmitters. Drugs affecting these processes and current research on receptor isolation and receptor mechanisms will be discussed from a chemical viewpoint. (Same as BIOL 775, CHEM 775, NURO 775, P&TX 775, and PHCH 775.) Prerequisite: Consent of instructor. LEC
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MDCM 777: Advanced Laboratory Techniques in Medicinal Chemistry (2 )
A laboratory course designed to acquaint advanced undergraduate and beginning graduate students with laboratory safety, the research notebook, use of advanced instrumental techniques for structural assignment and verification, methods of separation and purification, and the use of advanced reagents and laboratory transformations relevant to research in medicinal chemistry. Prerequisite: Consent of instructor. LAB
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MDCM 785: Natural Products of Medicinal Significance (2 )
A discussion of bioassay-directed screening, the isolation, structure determination, biosynthesis, partial synthesis and total chemical synthesis of organic natural products of medicinal significance. Examples of the classes of compounds to be considered include steroid hormones, cardiac glycosides, alkaloids, antibiotics, terpenes, and the like. Prerequisite: Graduate standing or consent of instructor. LEC
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MDCM 790: Principles of Drug Design (3 )
A discussion of the principles of contemporary drug design with specific examples chosen from the original literature. Prodrugs; bioisosteres; Kcat inhibitors; active site directed reversible and irreversible inhibitors; quantitative SAR; modulation of drug absorption, distribution, metabolism and excretion; molecular dissection; rigid analogs; pharmacophores; etc., will be treated. Prerequisite: Graduate standing or completion of MDCM 624 and MDCM 627. LEC
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MDCM 791: Principles of Drug Disposition (1 )
An introduction to the chemical and biochemical principles which govern the interaction of drugs and chemicals with cells and organisms. Topics include absorption, distribution, metabolism, and excretion; passive vs. active processes; pharmacokinetics; bioactivation vs. detoxication; and applications in drug design and improvement. Prerequisite: One year of organic chemistry and one course in biochemistry. LEC
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MDCM 795: Principles of Drug Design II (2 )
A discussion of the principles of contemporary drug design with specific examples chosen from the original literature. Drug-like properties; conformational constraint; structure-based drug design; library generation; HTS hit optimization, will be treated. LEC
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MDCM 799: Seminar in Medicinal Chemistry (1 )
Reports by research students and discussions of developments in the field not covered in formal courses. LEC
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MDCM 801: Issues in Scientific Integrity (1 )
Lectures and discussion on ethical issues in the conduct of a scientific career, with emphasis in the conduct of a scientific career, with emphasis on practical topics of special importance in molecular-level research in the chemical, biological, and pharmaceutical sciences. Topics will include the nature of ethics, the scientists in the laboratory, the scientist as author, grantee, reviewer, employer/employee, teacher, student, and citizen. Discussions will focus on case histories. Graded on a satisfactory/unsatisfactory basis. (Same as MDCM 801, NURO 801, P&TX 801, PHCH 801 and PHCH 802.) LEC
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MDCM 804: Interdisciplinary Seminar on Ethics in Science and Engineering (1-3 )
The course will cover basic techniques of moral reasoning, especially as applied to ethical issues in the physical sciences and engineering. Topics covered will include the ethical conduct of research, the federal and professional guidelines for different kinds of research, and the ethical dimensions of publication and professional life. Emphasis will be on practical applications, cases and student involvement. (Same as GS 804, NURO 804, P&TX 804, and PHCH 804.) Prerequisite: Must be admitted to the program or division of Pharmacy to enroll in this class. LEC
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MDCM 860: Drug Metabolism (2 )
An in-depth examination of the pathways, enzymes, and mechanisms of xenobiotic biotransformation in a combined lecture-readings-discussion format. Emphasis will be on recent as well as classic methods of findings. Prerequisite: MDCM 790 or MDCM 791 or consent of instructor. LEC
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MDCM 861: Drug Metabolism Laboratory (1-3 )
A laboratory course exemplifying various techniques used in studying the metabolism of foreign organic compounds in mammalian systems. In addition, enzymatic reactions in other plant and microbial systems are studied. Prerequisite: Consent of instructor. LAB
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MDCM 895: Research in Medicinal Chemistry (1-12 )
Hours and credit to be arranged. RSH
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MDCM 899: Master's Thesis (1-12 )
Hours and credit to be arranged. Independent investigation of a research problem of limited scope. Prerequisite: Consent of instructor. THE
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MDCM 950: Advanced Topics: _____ (1-3 )
An in-depth discussion of topics of current interest to medicinal chemists. Prerequisite: Consent of instructor. LEC
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MDCM 952: Introduction to Molecular Modeling (3 )
Theory and practice of contemporary molecular modeling: real-time computer graphics, model-building routines, use of structural databases, molecular mechanics and molecular dynamics calculations. The laboratory section places emphasis on drug design; work on own problems is welcome. (Same as BIOL 952.) Prerequisite: Graduate standing or consent of instructor. LAB
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MDCM 980: Original Research Proposal (2 )
Preparation of an original research proposal concerning contemporary problems in medicinal chemistry. Prerequisite: Consent of instructor. LAB
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MDCM 990: Postdoctoral Research in Medicinal Chemistry (1-12 )
Advanced level research in collaboration with a faculty member, which may involve projects in one or more of the following areas: organic synthesis, isolation and structure elucidation, metabolism, biochemical mechanisms of drug action. Prerequisite: Doctoral degree or equivalent in an appropriate related area, and consent of instructor. RSH
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MDCM 999: Doctoral Dissertation (1-12 )
Hours and credit to be arranged. Original chemical research in the synthesis and development of medicinal agents, elucidation of the chemical mechanisms of drug action, drug metabolism, and drug toxicities. THE
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NURO 710: Advanced Neurobiology (3 )
The course will build an in depth knowledge about basic mechanisms of synaptic communication among nerve cells and their targets, and the structure and function of nervous systems. Topics will include nervous system development and synapse formation, structure and function of neurons, physiological and molecular basis of synaptic communication between neurons, mechanisms of synaptic plasticity involved in learning and memory, sensory systems (vision, auditory, vestibular, motor reflexes and pain), processing of neural information at cellular and system levels, synapse regeneration and diseases of the nervous system. Prerequisite: BIOL 435 (Introduction to Neurobiology), or consent of instructor. LEC
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NURO 775: Chemistry of the Nervous System (3 )
A detailed study of the molecular aspects of nerve transmission will be covered with special emphasis on the uptake, storage, release, biosynthesis, and metabolism of specific neurotransmitters. Drugs affecting these processes and current research on receptor isolation and receptor mechanisms will be discussed from a chemical viewpoint. (Same as BIOL 775, CHEM 775, MDCM 775, P&TX 775, and PHCH 775.) Prerequisite: BIOL 600 or equivalent. LEC
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NURO 799: Neuroscience Seminar Series (2 )
Presentations of research papers by faculty, post-doctoral research associates, and graduate students. All graduate students in the Neuroscience program participate in this seminar series throughout their period of training. Each student has to present a seminar once every semester. Presentations by students are evaluated by other graduate students and faculty at the end of each seminar. Prerequisite: Graduate standing in the Neuroscience program. LEC
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NURO 800: Neuroscience Teaching Principles (2 )
This course is to be used by graduate students fulfilling the teaching requirements for the Ph.D. in Neuroscience. The student will function as a discussion leader and lecturer in a limited number of class sessions. Each student will meet with faculty whom he or she is assisting in preparation of presentation materials and tests. Each student will be evaluated by the faculty mentor and by the students in the class taught. Prerequisite: Graduate standing in Neuroscience. LEC
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NURO 801: Issues in Scientific Integrity (1 )
Lectures and discussion on ethical issues in the conduct of a scientific career, with emphasis on practical topics of special importance in molecular-level research in the chemical, biological, and pharmaceutical sciences. Topics will include the nature of ethics, the scientist in the laboratory, the scientist as author, grantee, reviewer, employer/employee, teacher, student, and citizen. Discussions will focus on case histories. Graded on a satisfactory/unsatisfactory basis. (Same as MDCM 801, P&TX 801, PHCH 801 and PHCH 802.) Prerequisite: Graduate standing in the Neuroscience program. LEC
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NURO 804: Interdisciplinary Seminar on Ethics in Science and Engineering (1-3 )
The course will cover basic techniques of moral reasoning, especially as applied to ethical issues in the physical sciences and engineering. Topics covered will include the ethical conduct of research, the federal and professional guidelines for different kinds of research, and the ethical dimensions of publication and professional life. Emphasis will be on practical applications, cases and student involvement. (Same as GS 804, MDCM 804, P&TX 804, and PHCH 804.) Prerequisite: Must be admitted to the program or division of Pharmacy to enroll in this class. LEC
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NURO 825: Research in Neuroscience (1-10 )
Original investigations at an advanced level in the areas of neuroscience. The research by each student will be performed in the laboratory of one of the faculty mentors of the graduate program in Neuroscience. Prerequisite: Graduate standing in the Neuroscience program. LEC
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NURO 844: Neurophysiology (3 )
Somatosensory, motor and cognitive function of the brain will be discussed using a combination of lecture and student presentation formats. Current issues and evidence underlying accepted concepts and mechanisms will be emphasized. (Same as PHSL 844.) Prerequisite: PHSL 846 or equivalent and consent of instructor. LEC
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NURO 846: Advanced Neuroscience (5 )
Team-taught, in-depth neuroscience course focusing on normal and diseased brain function at the molecular, cellular and systems levels. Lectures and discussions will emphasize current issues in neuroscience research. (Same as ANAT 846, PHCL 846, and PHSL 846.) Prerequisite: Permission of the course instructor. LEC
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NURO 847: Developmental Neurobiology (2 )
Development of the nervous system from early induction to the development of learning and memory. Topics include: Induction; Cellular Differentiation; Axon Growth and Guidance; Target Selection; Cell Survival and Growth; Synapse Formation; Synapse Elimination; and Development of Behavior. (Same as ANAT 847 and PHSL 847.) Prerequisite: Advanced Neuroscience (ANAT 846; NURO 846; PHSL 846) or consent of instructor. LEC
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NURO 848: Molecular Mechanisms of Neurological Disorders (3 )
An in-depth coverage of pathogenic mechanisms in neurological diseases; cellular and molecular responses to brain injury and disease, neuroinflammatory diseases (e.g., multiple sclerosis), neurodegenerative diseases (e.g., Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases), neurogenetic diseases (e.g., lysosomal and peroxisomal disorders, Down's syndrome and fragile X), trauma, stroke, and viral diseases (e.g., HIV encephalitis). (Same as ANAT 848, PHCL 848, and PHSL 848.) Prerequisite: Advanced Neuroscience (ANAT 846, PHCL 846 or PHSL 846) or an equivalent course and consent of instructor. LEC
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NURO 899: Neuroscience Master's Thesis (1-11 )
Hours and credit for this course to be arranged with the mentor. Independent investigation of a research problem in neuroscience, but of limited scope. Prerequisite: Graduate standing in the Neuroscience program and consent of mentor/instructor. THE
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NURO 999: Neuroscience Doctoral Dissertation (1-11 )
Hours and credit for this course to be arranged with the mentor. Conduct of original investigation in neurosciences. Prerequisite: Graduate standing in the Neuroscience program post-oral comprehensive examination and consent of mentor/instructor. THE
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P&TX 599: Clinical Application of Basic Science (1 )
This course is an inter-departmental, team-based, technology-centric elective course. Concomitantly, instructors from the basic and clinical science departments within the school of pharmacy will promote deeper student understanding of the path a drug takes from discovery, development and ultimately clinical use. Instructors will collaborate in course content development to integrate basic and clinical science concepts. The course will utilize a blended learning method, incorporating out of class podcasts, online group collaborative projects, and readiness quizzes and exams. (Same as MDCM 599 and PHCH 599.) Prerequisite: 4th or 5th professional year standing (4P/5P) in the school of pharmacy and concomitant enrollment in PHPR 599 is required. LEC
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P&TX 630: Pharmacology I (4 )
The pharmacology series covers the mechanisms by which drugs interact with living organisms. An integrative emphasis will be placed on understanding the molecular basis of drug action with respect to modifying the pathophysiology of specific disease states. Topics in P&TX 630 include, general principles of cell biology, molecular biology, pharmacogenomics, immunology and principles of drug metabolism and disposition. Prerequisite: BIOL 646 or equivalent. LEC
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P&TX 631: Pharmacology II (4 )
The pharmacology series covers the mechanisms by which drugs interact with living organisms. An integrative emphasis will be placed on understanding the molecular basis of drug action with respect to modifying the pathophysiology of specific disease states. Topics in P&TX 631 include, hematology, cancer biology and therapeutics, immunopharmacology, infectious diseases and respiratory disease. Prerequisite: P&TX 630 and BIOL 400 or equivalent. LEC
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P&TX 632: Pharmacology III (4 )
The pharmacology series covers the mechanisms by which drugs interact with living organisms. An integrative emphasis will be placed on understanding the molecular basis of drug action with respect to modifying the pathophysiology of specific disease states. Topics in P&TX 632 include, cardiovascular diseases, diuretics, autonomic pharmacology and drugs regulating central nervous system function. Prerequisite: P&TX 630 and P&TX 631. LEC
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P&TX 633: Pharmacology IV (3 )
The pharmacology series covers the mechanisms by which drugs interact with living organisms. An integrative emphasis will be placed on understanding the molecular basis of drug action with respect to modifying the pathophysiology of specific disease states. Topics in P&TX 633 include endocrine disorders, diabetes and obesity, and gastrointestinal pharmacology. Prerequisite: P&TX 630, P&TX 631 and P&TX 632. LEC
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P&TX 640: Toxicology (2 )
General principles of toxicology, treatment, and management of accidental poisoning, and current topics of interest. Prerequisite: P&TX 630, P&TX 631, and P&TX 632. LEC
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P&TX 641: Antibiotics: Benefits and Risks (1 )
Students will read about and discuss the latest research on new antibiotic targets, therapeutic potential, disease prevention, and the emergence of antibiotic resistance. LEC
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P&TX 642: Obesity, Diabetes, and Metabolic Syndrome: Current Concepts (1 )
The objective of this course is to provide students with an opportunity to read, examine, and report on a broad array of topics relevant to diabetes and obesity. Students will be given broad latitude to propose topics of interest to them within the area of diabetes and obesity. The format of the course will be group presentations. Groups of 3 students will identify a topic of interest to them in the field of diabetes and obesity, prepare a 30 min presentation and deliver it to the class for discussion. Prerequisite: P&TX 630. LEC
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P&TX 643: Current Concepts of Neurodegenerative Disease (1 )
Neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases, are associated with older age and/or enhanced oxidative stress. The possible causes for the development and progression of these diseases with relation to current research in the field will be discussed. Additionally, a summary of available and suggested future treatments will be given. Prerequisite: P&TX 630. LEC
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P&TX 644: Adverse Drug Events (1 )
The objective of this course is to alerts students to common and preventable adverse drug events. This course will provide students with an opportunity to read, examine, and report on a broad array of topics relevant to adverse drug events. Students will be given broad latitude to propose topics of interest to them within the area of adverse drug events. In addition students can report on common and preventable food-drug, herb-drug, and disease-drug interactions. The format of the course will be group presentations. Groups of 3 students will identify a topic of interest to them among a list of provided topics, prepare a 30 minute presentation and deliver it to the class for discussion. Prerequisite: 3rd, 4th, or 5th professional year standing in the School of Pharmacy. LEC
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P&TX 645: Neurobiological Basis of Addiction: Physiological, Biochemical, Pharmacological & Treatment Concepts (1 )
Several addictions will be discussed including addictions to alcohol, cocaine, methamphetamine, gambling, and others as time permits. The physiology, biochemistry, pharmacology and available treatments for these addictions will be reviewed. The role of pharmacotherapies will be discussed, particularly as they relate to the molecular basis of addiction. Behavioral and psychological approaches also will be examined. Prerequisite: Completion of P&TX 632 or special permission from faculty. LEC
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P&TX 694: Undergraduate Laboratory: Research in Pharmacology and Toxicology (1-5 )
Original research on a laboratory problem of limited scope. This course cannot count toward pharmacology and toxicology requirements in the School of Pharmacy. Prerequisite: Consent of instructor. IND
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P&TX 698: Library Problems in Pharmacology and Toxicology (1-5 )
Original library review of a limited special topic in pharmacology and toxicology. The student will write a review in his or her report. This course may count toward pharmacology and toxicology requirements in the School of Pharmacy. Prerequisite: P&TX 635 and consent of instructor. IND
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P&TX 700: Professional Issues in the Biomedical Sciences (2 )
A course designed to assist doctoral students in the biomedical sciences in their professional development by providing presentations, discussions, and practical experiences related to career planning. Topics include diverse career opportunities and expectations of each, preparation of vitae/resumes and other elements of a successful job search, writing scientific papers and dealing with editors, developing programmatic research programs, balancing professional obligations, advancing through promotions, and related topics. Prerequisite: Graduate standing in pharmacology and toxicology. LEC
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P&TX 710: Behavioral Neurobiology (3 )
This course will examine the bases for reciprocal dynamic interactions between central nervous system function and structure ("nature") and experience ("nurture"). "Nature" will be explored using principles and methodologies derived from systems and molecular pharmacology, and neurochemistry. The effects of "nurture" on brain will involve issues derived from behavioral pharmacology, environmental enrichment, and human brain imaging. During the course, with the help of the instructor, students will be expected to discuss and critically analyze research articles for subsequent presentation to the class. LEC
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P&TX 725: Biomedical Bibliography (1 )
The use of the library as a research tool and the study of bibliographic techniques of literature searching. Emphasis on pharmacological, physiological, biochemical, and medical literature. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Graduate standing. LEC
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P&TX 730: Advanced Pharmacology I - CNS and ANS (2 )
A detailed study of the fundamentals of autonomic nervous system, central nervous system, and their pharmacology. The student will attend P&TX 632 lectures and meet separately with the faculty for additional discussions of advanced material on the topics. The students will be examined on the advanced material. Prerequisite: Graduate standing in Pharmacology and Toxicology Program. LEC
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P&TX 731: Advanced Pharmacology II - Cardiovascular and Renal System (2 )
A detailed study of the fundamentals of cardiovascular system, renal system and their pharmacology. The student will attend P&TX 632 lectures and meet separately with the faculty for additional discussions of advanced material on the topics. The students will be examined on the advanced material. Prerequisite: Graduate standing in Pharmacology and Toxicology Program. LEC
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P&TX 732: Advanced Pharmacology III - Cancer Biology and Inflammatory Diseases (2 )
A detailed study of the fundamentals of inflammation, cancer biology and their pharmacology. The student will attend P&TX 631 lectures and meet separately with the faculty for additional discussions of advanced material on the topics. The students will be examined on the advanced material. Prerequisite: Graduate standing in Pharmacology and Toxicology Program. LEC
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P&TX 733: Advanced Pharmacology IV - Endocrinology (2 )
A detailed study of the fundamentals of endocrinology and associated pharmacology. The student will attend P&TX 633 lectures and meet separately with the faculty for additional discussions of advanced material on the topics. The students will be examined on the advanced material. Prerequisite: Graduate standing in Pharmacology and Toxicology Program. LEC
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P&TX 740: Advanced Biotechnology (3 )
An examination of basic principles of molecular biology, immunology, and protein chemistry as they apply to the identification, production, stability, delivery, and monitoring of new therapeutic agents provided by the expanding biotechnology industry. Students will attend lectures in P&TX 633 and meet separately with faculty for additional discussions of more advanced material on these topics. The students will be examined on the advanced material. Prerequisite: Graduate standing in Pharmacology and Toxicology. LAB
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P&TX 742: Experimental Pharmacology (4 )
Experimental approaches to understanding mechanism of drug action. Use of drugs as tools to understand functioning of biological systems will also be stressed. Historically important experiments will be discussed along with experiments which are currently used to define drug mechanisms. Topics will include: dose-response, drug receptors, drug metabolism, chemotherapy as well as autonomic CNS, cardiovascular and renal pharmacology. Prerequisite: Graduate standing in Pharmacology and Toxicology Program. LEC
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P&TX 747: Molecular Toxicology (4 )
A detailed study of the fundamentals of the experimental methods used in a modern toxicology laboratory. The student will attend P&TX 640 lectures and meet separately with the faculty for additional discussions of advanced material on the topics. The students will be examined on the advanced material. Prerequisite: Graduate standing in Pharmacology and Toxicology Program. LEC
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P&TX 775: Chemistry of the Nervous System (3 )
A detailed study of the molecular aspects of nerve transmission will be covered with special emphasis on the uptake, storage, release, biosynthesis, and metabolism of specific neurotransmitters. Drugs affecting these processes and current research on receptor isolation and receptor mechanisms will be discussed from a chemical viewpoint. (Same as BIOL 775, CHEM 775, MDCM 775, NURO 775, and PHCH 775.) Prerequisite: BIOL 600 or equivalent. LEC
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P&TX 799: Pharmacology and Toxicology Seminar (1-2 )
A review of current literature and research in pharmacology and toxicology. Required of all graduate students in the department every fall and spring semester. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Graduate standing in P&TX. LEC
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P&TX 800: Pharmacology and Toxicology Teaching Principles (2 )
This course is to be used by graduate students fulfilling the teaching requirements for the Ph.D. in pharmacology and toxicology. The student will function as a discussion leader and lecturer in a limited number of class sessions. Each student will meet with the faculty whom he or she is assisting. Prerequisite: Graduate standing in pharmacology and toxicology program. RSH
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P&TX 801: Issues in Scientific Integrity (1-3 )
Lectures and discussion on ethical issues in the conduct of a scientific career, with emphasis on practical topics of special importance in molecular-level research in the chemical, biological, and pharmaceutical sciences. Topics will include the nature of ethics, the scientist in the laboratory, the scientist as author, grantee, reviewer, employer/employee, teacher, student, and citizen. Discussions will focus on case histories. Graded on a satisfactory/unsatisfactory basis. (Same as MDCM 801, NURO 801, PHCH 801 and PHCH 802.) LEC
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P&TX 803: Pharmacology Literature Review I (1 )
This course is designed for graduate students and will fulfill the first written exam requirement for the Ph.D. in pharmacology and Toxicology. The student will research and write a six page literature review by choosing a topic provided by the faculty. Prerequisite: Graduate standing in Pharmacology and Toxicology Program. LEC
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P&TX 804: Interdisciplinary Seminar on Ethics in Science and Engineering (1-3 )
The course will cover basic techniques of moral reasoning, especially as applied to ethical issues in the physical sciences and engineering. Topics covered will include the ethical conduct of research, the federal and professional guidelines for different kinds of research, and the ethical dimensions of publication and professional life. Emphasis will be on practical applications, cases and student involvement. (Same as GS 804, MDCM 804, NURO 804, and PHCH 804.) Prerequisite: Must be admitted to the program or division of Pharmacy to enroll in this class. LEC
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P&TX 805: Pharmacology Literature Review II (1 )
This course is designed for graduate students and will fulfill the second written exam requirement for the Ph.D. in pharmacology and Toxicology. The student will research and write a twelve page literature review by choosing a topic provided by the faculty. Prerequisite: Graduate standing in Pharmacology and Toxicology Program. LEC
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P&TX 825: Research in Pharmacology and Toxicology (1-10 )
Original investigations at an advanced level in the areas of pharmacology or toxicology or related fields. This research will be performed by graduate students in collaboration with a faculty member. Prerequisite: Graduate standing and consent of instructor. RSH
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P&TX 899: Master's Thesis (1-11 )
Hours and credit to be arranged. Independent investigation of a research problem of limited scope. Prerequisite: Graduate standing in P&TX and consent of instructor. THE
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P&TX 901: Seminar: Psychotropic Drugs Across the Lifespan (3 )
Through the use of both traditional didactic and student participatory instructional methods, the seminar will address basic pharmacological concepts (i.e., assimilation, distribution, elimination, dose effect analyses, kinetics, etc.), neuropharmacological principles (i.e., neuronal mechanisms of action of psychotropic drugs, animal models of human psychiatric disorders, etc.), and therapeutics (i.e., drug treatment of psychosis, depression, Alzheimer's disease, etc.). Special attention will be devoted to the organism's age (and history) as these may influence psychopharmacological outcomes. LEC
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P&TX 902: Behavioral Neurobiology (3 )
This course will examine the bases for reciprocal dynamic interactions between central nervous system function and structure ("nature") and experience ("nurture"). "Nature" will be explored using principles and methodologies derived from systems and molecular pharmacology, and neurochemistry. The effects of "nurture" on brain will involve issues derived from behavioral pharmacology, environmental, enrichment, and human brain imaging. During the course, with the help of the instructor, students will be expected to discuss and critically analyze research articles for subsequent presentation to the class. LEC
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P&TX 950: Molecular Pharmacology (2 )
A study of drug effects at the cellular, subcellular, and molecular levels, and the correlation with tissue and organ reactions. Prerequisite: Graduate standing in P&TX and consent of instructor. LEC
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P&TX 990: Postdoctoral Research (1-11 )
Advanced level research in collaboration with a faculty member in the department. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Doctoral degree or equivalent in an appropriate related area, and consent of instructor. RSH
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P&TX 999: Doctoral Dissertation (1-11 )
Hours and credit to be arranged. Original investigation in pharmacology and toxicology. Prerequisite: Consent of instructor. THE
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PHAR 500: Early Pharmacy Practice Experience (1 )
PHAR 500 is a didactic course designed to introduce the student pharmacist to the concepts of Introductory Pharmacy Practice Experiential Education, fulfill pre-requisites needed prior to IPPE site placement and to prepare the student for participation in the Introductory Pharmacy Practice Experiences. The course will address topics such as professionalism, confidentiality, patient interaction, medical and drug histories, blood borne pathogens and CPR. Students must be accepted to the school of pharmacy to be eligible to enroll. FLD
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PHAR 503: Pharmacy Practice III Health-System Pharmacy Practice Fundamentals (3 )
Introduction to the prescription dispensing process within health-system pharmacies (hospital, nursing home, home health, HMO) with an emphasis on distribution systems, parenteral, and sterile products. Incorporates lectures, case studies, pharmacy visits and laboratory experience. Prerequisite: PHPR 502. LEC
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PHAR 505: Immunization Theory and Practice (1 )
This course will provide students with the training and resources/materials necessary to: a) identify at-risk patient populations needing immunizations, b) work with other health-care professionals to establish and promote a successful pharmacy-based immunization service, c) act as either vaccine advocate or immunizer when appropriate, and d) promote public health by helping the patients they serve avoid vaccine-preventable communicable diseases. LEC
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PHAR 507: Dean's Orientation and Introduction to Pharmacy (1 )
An introduction to the profession of pharmacy addressing issues such as 1) academic expectations, 2) professional expectations, 3) ethics, 4) various career pathways, and 5) medical communication. Students must be accepted to the school of pharmacy to be eligible to enroll. LEC
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PHAR 509: History of Pharmacy Elective (1 )
This course is comprised of a survey of historical highlights of the development of Pharmacy as a discipline. The course will cover early antecedents of pharmacy, development of the discipline in Europe and the United States, the development of professional organizations, standards, education, and literature, economic development, and the pharmacists' contributions to community service, science, and the industry. There will be a mix of some lectures, discussion, assigned readings, and short papers. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Must be accepted to the Pharmacy Program. LEC
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PHAR 510: Pharmacy Skills Laboratory I (1 )
Exercises that reinforce the concepts taught in pharmacy practice, pharmaceutical chemistry, medicinal chemistry, and pharmacology courses. Includes exercises in compounding, dispensing and patient counseling. LAB
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PHAR 515: Pharmacy Skills Laboratory II (1 )
Exercises that reinforce the concepts taught in pharmacy practice, pharmaceutical chemistry, medicinal chemistry, and pharmacology courses. Includes exercises in compounding, dispensing, and patient counseling. LAB
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PHAR 520: Pharmacy Skills Laboratory III (1 )
Exercises that reinforce the concepts taught in pharmacy practice, pharmaceutical chemistry, medicinal chemistry, and pharmacology courses. Includes exercises in compounding, dispensing, and patient counseling. LAB
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PHAR 525: Pharmacy Skills Laboratory IV (1 )
Exercises that reinforce the concepts taught in pharmacy practice, pharmaceutical chemistry, medicinal chemistry, and pharmacology courses. Includes exercises in compounding, dispensing, and patient counseling. LAB
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Contact Info

School of Pharmacy

2010 Becker Drive, Room 2050
Lawrence, KS 66047-1620
785-864-3591
785-864-5265
pharmacy@ku.edu
http://www.pharm.ku.edu/
Kenneth L. Audus, Dean
785-864-3591
Gene Hotchkiss, Senior Associate Dean, Administration
785-864-3591

School of Pharmacy

2010 Becker Drive, Room 2050
Lawrence, KS 66047-1620
785-864-3591
785-864-5265
pharmacy@ku.edu
http://www.pharm.ku.edu/
Brian J. Barnes, Associate Dean, Academic Affairs
785-864-3591

School of Pharmacy

2010 Becker Drive, Room 2050
Lawrence, KS 66047-1620
785-864-3591
785-864-5265
pharmacy@ku.edu
http://www.pharm.ku.edu/
John F. Stobaugh, Associate Dean, Research and Graduate Affairs
785-864-3591
Why KU
  • One of 34 public institutions in the prestigious Association of American Universities
  • 2nd in the nation for prestigious faculty Fulbright awards
  • 26 Rhodes scholars
  • Nearly $290 million in financial aid annually
  • One of 9 public universities with outstanding study abroad programs. U.S. News and World Report